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MCR-1 Inhibition with Peptide-Conjugated Phosphorodiamidate Morpholino Oligomers Restores Sensitivity to Polymyxin in Escherichia coli

In late 2015, the first example of a transferrable polymyxin resistance mechanism in Gram-negative pathogens, MCR-1, was reported. Since that report, MCR-1 has been described to occur in many Gram-negative pathogens, and the mechanism of MCR-1-mediated resistance was rapidly determined: an ethanolam...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Daly, Seth M., Sturge, Carolyn R., Felder-Scott, Christina F., Geller, Bruce L., Greenberg, David E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5676038/
https://ncbi.nlm.nih.gov/pubmed/29114023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01315-17
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