Experimental Human Challenge Defines Distinct Pneumococcal Kinetic Profiles and Mucosal Responses between Colonized and Non-Colonized Adults

Colonization of the upper respiratory tract with Streptococcus pneumoniae is the precursor of pneumococcal pneumonia and invasive disease. Following exposure, however, it is unclear which human immune mechanisms determine whether a pathogen will colonize. We used a human challenge model to investiga...

詳細記述

保存先:
書誌詳細
出版年:mBio
主要な著者: Nikolaou, Elissavet, Jochems, Simon P., Mitsi, Elena, Pojar, Sherin, Blizard, Annie, Reiné, Jesus, Solórzano, Carla, Negera, Edessa, Carniel, Beatriz, Soares-Schanoski, Alessandra, Connor, Victoria, Adler, Hugh, Zaidi, Seher R., Hales, Caz, Hill, Helen, Hyder-Wright, Angie, Gordon, Stephen B., Rylance, Jamie, Ferreira, Daniela M.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2021
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7844534/
https://ncbi.nlm.nih.gov/pubmed/33436429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02020-20
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