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The Digenic Causality in Familial Hypercholesterolemia: Revising the Genotype–Phenotype Correlations of the Disease

Genetically inherited defects in lipoprotein metabolism affect more than 10 million individuals around the globe with preponderance in some parts where consanguinity played a major role in establishing founder mutations. Mutations in four genes have been so far linked to the dominant and recessive f...

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Bibliographische Detailangaben
Veröffentlicht in:Front Genet
Hauptverfasser: Kamar, Amina, Khalil, Athar, Nemer, Georges
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7844333/
https://ncbi.nlm.nih.gov/pubmed/33519890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2020.572045
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