Detection of Low-Frequency KRAS Mutations in cfDNA From EGFR-Mutated NSCLC Patients After First-Line EGFR Tyrosine Kinase Inhibitors

BACKGROUND: Molecular profiling of advanced EGFR mutated NSCLC has recently demonstrated the co-existence of multiple genetic alterations. Specifically, co-existing KRAS-mutations in EGFR NSCLCs have been described, despite their prevalence at progression and their role in the response to EGFR tyros...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Nardo, Giorgia, Carlet, Jessica, Marra, Ludovica, Bonanno, Laura, Boscolo, Alice, Dal Maso, Alessandro, Boscolo Bragadin, Andrea, Indraccolo, Stefano, Zulato, Elisabetta
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7844327/
https://ncbi.nlm.nih.gov/pubmed/33520716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.607840
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