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Detection of Loss of Heterozygosity in cfDNA of Advanced EGFR- or KRAS-Mutated Non-Small-Cell Lung Cancer Patients

Liquid biopsy is currently approved for management of epidermal growth factor receptor (EGFR)-mutated non-small-cell lung cancer (NSCLC) patients. However, one unanswered question is whether the rate of cell-free DNA (cfDNA)-negative samples is due to technical limitations rather than to tumor genet...

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Библиографические подробности
Опубликовано в: :Int J Mol Sci
Главные авторы: Boldrin, Elisa, Nardo, Giorgia, Zulato, Elisabetta, Bonanno, Laura, Polo, Valentina, Frega, Stefano, Pavan, Alberto, Indraccolo, Stefano, Saggioro, Daniela
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2019
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6981934/
https://ncbi.nlm.nih.gov/pubmed/31861832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21010066
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