Hierarchical Modelling of Haplotype Effects on a Phylogeny

We introduce a hierarchical model to estimate haplotype effects based on phylogenetic relationships between haplotypes and their association with observed phenotypes. In a population there are many, but not all possible, distinct haplotypes and few observations per haplotype. Further, haplotype freq...

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Bibliografiske detaljer
Udgivet i:Front Genet
Main Authors: Selle, Maria Lie, Steinsland, Ingelin, Lindgren, Finn, Brajkovic, Vladimir, Cubric-Curik, Vlatka, Gorjanc, Gregor
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Genetics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7844322/
https://ncbi.nlm.nih.gov/pubmed/33519886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2020.531218
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