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Robust modeling of additive and nonadditive variation with intuitive inclusion of expert knowledge
We propose a novel Bayesian approach that robustifies genomic modeling by leveraging expert knowledge (EK) through prior distributions. The central component is the hierarchical decomposition of phenotypic variation into additive and nonadditive genetic variation, which leads to an intuitive model p...
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| Publicado no: | Genetics |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8045730/ https://ncbi.nlm.nih.gov/pubmed/33789346 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/genetics/iyab002 |
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