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Utility of Zebrafish Models of Acquired and Inherited Long QT Syndrome

Long-QT Syndrome (LQTS) is a cardiac electrical disorder, distinguished by irregular heart rates and sudden death. Accounting for ∼40% of cases, LQTS Type 2 (LQTS2), is caused by defects in the Kv11.1 (hERG) potassium channel that is critical for cardiac repolarization. Drug block of hERG channels o...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Simpson, Kyle E., Venkateshappa, Ravichandra, Pang, Zhao Kai, Faizi, Shoaib, Tibbits, Glen F., Claydon, Tom W.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7844309/
https://ncbi.nlm.nih.gov/pubmed/33519527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2020.624129
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