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In Vitro and In Silico Risk Assessment in Acquired Long QT Syndrome: The Devil Is in the Details

Acquired long QT syndrome, mostly as a result of drug block of the Kv11. 1 potassium channel in the heart, is characterized by delayed cardiac myocyte repolarization, prolongation of the T interval on the ECG, syncope and sudden cardiac death due to the polymorphic ventricular arrhythmia Torsade de...

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Publicat a:Front Physiol
Autors principals: Lee, William, Windley, Monique J., Vandenberg, Jamie I., Hill, Adam P.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5696636/
https://ncbi.nlm.nih.gov/pubmed/29201009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2017.00934
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