Inhibition of the CXCL9-CXCR3 axis suppresses the progression of experimental apical periodontitis by blocking macrophage migration and activation

Apical periodontitis (AP) is an acute or chronic inflammatory disease caused by complex interactions between infected root canal and host immune system. It results in the induction of inflammatory mediators such as chemokines and cytokines leading to periapical tissue destruction. To understand the...

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Publicat a:Sci Rep
Autors principals: Hasegawa, Tatsuya, Venkata Suresh, V., Yahata, Yoshio, Nakano, Masato, Suzuki, Shigeto, Suzuki, Shigeki, Yamada, Satoru, Kitaura, Hideki, Mizoguchi, Itaru, Noiri, Yuichiro, Handa, Keisuke, Saito, Masahiro
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7844264/
https://ncbi.nlm.nih.gov/pubmed/33510341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-82167-7
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