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Inhibition of the CXCL9-CXCR3 axis suppresses the progression of experimental apical periodontitis by blocking macrophage migration and activation

Apical periodontitis (AP) is an acute or chronic inflammatory disease caused by complex interactions between infected root canal and host immune system. It results in the induction of inflammatory mediators such as chemokines and cytokines leading to periapical tissue destruction. To understand the...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Hasegawa, Tatsuya, Venkata Suresh, V., Yahata, Yoshio, Nakano, Masato, Suzuki, Shigeto, Suzuki, Shigeki, Yamada, Satoru, Kitaura, Hideki, Mizoguchi, Itaru, Noiri, Yuichiro, Handa, Keisuke, Saito, Masahiro
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7844264/
https://ncbi.nlm.nih.gov/pubmed/33510341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-82167-7
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