Notch signaling-modified mesenchymal stem cells improve tissue perfusion by induction of arteriogenesis in a rat hindlimb ischemia model

Notch signaling-modified human mesenchymal stem cell, SB623 cell, is a promising cell therapy product for ischemic stroke. With the aim to expand indications for their use for critical limb-threatening ischemia (CLTI), we hypothesized that SB623 cells improved tissue perfusion by inducing angiogenes...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Maeda, Shusaku, Miyagawa, Shigeru, Kawamura, Takuji, Shibuya, Takashi, Watanabe, Kenichi, Nakagawa, Takaya, Harada, Akima, Chida, Dai, Sawa, Yoshiki
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7844258/
https://ncbi.nlm.nih.gov/pubmed/33510394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-82284-3
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