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High-throughput measurement of fibroblast rhythms reveals genetic heritability of circadian phenotypes in diversity outbred mice and their founder strains

Circadian variability is driven by genetics and Diversity Outbred (DO) mice is a powerful tool for examining the genetics of complex traits because their high genetic and phenotypic diversity compared to conventional mouse crosses. The DO population combines the genetic diversity of eight founder st...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kim, Sam-Moon, Vadnie, Chelsea A., Philip, Vivek M., Gagnon, Leona H., Chowdari, Kodavali V., Chesler, Elissa J., McClung, Colleen A., Logan, Ryan W.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7843998/
https://ncbi.nlm.nih.gov/pubmed/33510298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-82069-8
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