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High-throughput measurement of fibroblast rhythms reveals genetic heritability of circadian phenotypes in diversity outbred mice and their founder strains

Circadian variability is driven by genetics and Diversity Outbred (DO) mice is a powerful tool for examining the genetics of complex traits because their high genetic and phenotypic diversity compared to conventional mouse crosses. The DO population combines the genetic diversity of eight founder st...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Kim, Sam-Moon, Vadnie, Chelsea A., Philip, Vivek M., Gagnon, Leona H., Chowdari, Kodavali V., Chesler, Elissa J., McClung, Colleen A., Logan, Ryan W.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7843998/
https://ncbi.nlm.nih.gov/pubmed/33510298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-82069-8
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