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TET-Mediated Epigenetic Regulation in Immune Cell Development and Disease
TET proteins oxidize 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC) and further oxidation products in DNA. The oxidized methylcytosines (oxi-mCs) facilitate DNA demethylation and are also novel epigenetic marks. TET loss-of-function is strongly associated with cancer; TET2 loss-of-function...
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| Publicado en: | Front Cell Dev Biol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Frontiers Media S.A.
2021
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7843795/ https://ncbi.nlm.nih.gov/pubmed/33520997 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.623948 |
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