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Targeting evolution of antibiotic resistance by SOS response inhibition

Antibiotic resistance is acquired in response to antibiotic therapy by activating SOS-depended mutagenesis and horizontal gene transfer pathways. Compounds able to inhibit SOS response are extremely important to develop new combinatorial strategies aimed to block mutagenesis. The regulators of homol...

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Pubblicato in:Comput Struct Biotechnol J
Autori principali: Yakimov, Alexander, Bakhlanova, Irina, Baitin, Dmitry
Natura: Artigo
Lingua:Inglês
Pubblicazione: Research Network of Computational and Structural Biotechnology 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7843400/
https://ncbi.nlm.nih.gov/pubmed/33552448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2021.01.003
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