Zinc Blockade of SOS Response Inhibits Horizontal Transfer of Antibiotic Resistance Genes in Enteric Bacteria

The SOS response is a conserved response to DNA damage that is found in Gram-negative and Gram-positive bacteria. When DNA damage is sustained and severe, activation of error-prone DNA polymerases can induce a higher mutation rate than is normally observed, which is called the SOS mutator phenotype...

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Библиографические подробности
Опубликовано в: :Front Cell Infect Microbiol
Главные авторы: Crane, John K., Cheema, Muhammad B., Olyer, Michael A., Sutton, Mark D.
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2018
Предметы:
Cellular and Infection Microbiology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6258817/
https://ncbi.nlm.nih.gov/pubmed/30519543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2018.00410
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