Simvastatin Inhibits CYR61 Expression in Orbital Fibroblasts in Graves' Ophthalmopathy through the Regulation of FoxO3a Signaling

Graves' ophthalmopathy (GO), which is characterized by orbital tissue inflammation, expansion, and fibrosis, is the ocular manifestation in 25% to 50% of patients with Graves' disease. As the pathology of GO is driven by autoimmune inflammation, many proinflammatory cytokines/chemokines, i...

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Dades bibliogràfiques
Publicat a:Mediators Inflamm
Autors principals: Wei, Yi-Hsuan, Liao, Shu-Lang, Wang, Chia-Chun, Wang, Sen-Hsu, Tang, Wan-Chun, Yang, Chang-Hao
Format: Artigo
Idioma:Inglês
Publicat: Hindawi 2021
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7843182/
https://ncbi.nlm.nih.gov/pubmed/33542676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2021/8888913
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