Simvastatin downregulates adipogenesis in 3T3-L1 preadipocytes and orbital fibroblasts from Graves’ ophthalmopathy patients

BACKGROUND: Smoking is a strong risk factor for the development of Graves’ ophthalmopathy (GO). Immediate early genes (IEGs) are overexpressed in patients with active GO compared to healthy controls. The aim of this study was to study the effects of tobacco smoking and simvastatin on preadipocytes a...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Endocr Connect
Päätekijät: Shahida, B, Johnson, P Sahlstrand, Jain, R, Brorson, H, Åsman, P, Lantz, M, Planck, T
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Bioscientifica Ltd 2019
Aiheet:
Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6733370/
https://ncbi.nlm.nih.gov/pubmed/31394503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/EC-19-0319
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