Antagonism between germ cell-less and Torso receptor regulates transcriptional quiescence underlying germline/soma distinction

Transcriptional quiescence, an evolutionarily conserved trait, distinguishes the embryonic primordial germ cells (PGCs) from their somatic neighbors. In Drosophila melanogaster, PGCs from embryos maternally compromised for germ cell-less (gcl) misexpress somatic genes, possibly resulting in PGC loss...

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Udgivet i:eLife
Main Authors: Colonnetta, Megan M, Lym, Lauren R, Wilkins, Lillian, Kappes, Gretchen, Castro, Elias A, Ryder, Pearl V, Schedl, Paul, Lerit, Dorothy A, Deshpande, Girish
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2021
Fag:
Developmental Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7843132/
https://ncbi.nlm.nih.gov/pubmed/33459591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.54346
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