Germ cell-less promotes centrosome segregation to induce germ cell formation

The primordial germ cells (PGCs) specified during embryogenesis serve as progenitors to the adult germline stem cells. In Drosophila, the proper specification and formation of PGCs requires both centrosomes and germ plasm, which contains the germline determinants. Centrosomes are microtubule (MT)-or...

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Gepubliceerd in:Cell Rep
Hoofdauteurs: Lerit, Dorothy A., Shebelut, Conrad W., Lawlor, Kristen J., Rusan, Nasser M., Gavis, Elizabeth R., Schedl, Paul, Deshpande, Girish
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5327791/
https://ncbi.nlm.nih.gov/pubmed/28122234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.12.074
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