Bartonella type IV secretion effector BepC induces stress fiber formation through activation of GEF-H1

Bartonella T4SS effector BepC was reported to mediate internalization of big Bartonella aggregates into host cells by modulating F-actin polymerization. After that, BepC was indicated to induce host cell fragmentation, an interesting cell phenotype that is characterized by failure of rear-end retrac...

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Bibliographic Details
Published in:PLoS Pathog
Main Authors: Wang, Chunyan, Zhang, Haoran, Fu, Jiaqi, Wang, Meng, Cai, Yuhao, Ding, Tianyun, Jiang, Jiezhang, Koehler, Jane E., Liu, Xiaoyun, Yuan, Congli
Format: Artigo
Language:Inglês
Published: Public Library of Science 2021
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7842913/
https://ncbi.nlm.nih.gov/pubmed/33508039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1009065
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