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Preparation of a Bacteriophage T4-based Prokaryotic-eukaryotic Hybrid Viral Vector for Delivery of Large Cargos of Genes and Proteins into Human Cells

A viral vector that can safely and efficiently deliver large and diverse molecular cargos into cells is the holy grail of curing many human diseases. Adeno-associated virus (AAV) has been extensively used but has a very small capacity. The prokaryotic virus T4 has a large capacity but lacks natural...

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Detalhes bibliográficos
Publicado no:Bio Protoc
Main Authors: Zhu, Jingen, Tao, Pan, Mahalingam, Marthandan, Rao, Venigalla B.
Formato: Artigo
Idioma:Inglês
Publicado em: Bio-Protocol 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7842784/
https://ncbi.nlm.nih.gov/pubmed/33659543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21769/BioProtoc.3573
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