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Optogenetic Tuning of Ligand Binding to The Human T cell Receptor Using The opto-ligand-TCR System
T cells are one major cell type of the immune system that use their T cell antigen receptor (TCR) to bind and respond to foreign molecules derived from pathogens. The ligand-TCR interaction half-lives determine stimulation outcome. Until recently, scientists relied on mutating either the TCR or its...
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| Veröffentlicht in: | Bio Protoc |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Bio-Protocol
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7842703/ https://ncbi.nlm.nih.gov/pubmed/33659514 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21769/BioProtoc.3540 |
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