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Double Labeling of PDGFR-β and α-SMA in Swine Models of Acute Kidney Injury to Detect Pericyte-to-Myofibroblast Transdifferentation as Early Marker of Fibrosis

Growing evidences suggest that peritubular capillaries pericytes are the main source of scar-forming myofibroblasts during chronic kidney disease (CKD), as well as early phases of acute kidney injury (AKI). In a swine model of sepsis and I/R (Ischemia Reperfusion) injury-induced AKI we demonstrated...

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Detalhes bibliográficos
Publicado no:Bio Protoc
Main Authors: Stasi, Alessandra, Franzin, Rossana, Divella, Chiara, Gesualdo, Loreto, Stallone, Giovanni, Castellano, Giuseppe
Formato: Artigo
Idioma:Inglês
Publicado em: Bio-Protocol 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7842307/
https://ncbi.nlm.nih.gov/pubmed/33659435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21769/BioProtoc.3779
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