Heparin Accelerates the Protein Aggregation via the Downhill Polymerization Mechanism: Multi-Spectroscopic Studies to Delineate the Implications on Proteinopathies

[Image: see text] Heparin is one of the members of the glycosaminoglycan (GAG) family, which has been associated with protein aggregation diseases including Alzheimer’s disease, Parkinson’s disease, and prion diseases. Here, we investigate heparin-induced aggregation of bovine serum albumin (BSA) us...

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Bibliographic Details
Published in:ACS Omega
Main Authors: Ahanger, Ishfaq Ahmad, Parray, Zahoor Ahmad, Nasreen, Khalida, Ahmad, Faizan, Hassan, Md. Imtaiyaz, Islam, Asimul, Sharma, Anurag
Format: Artigo
Language:Inglês
Published: American Chemical Society 2021
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7841943/
https://ncbi.nlm.nih.gov/pubmed/33521471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.0c05638
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