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Heparin Accelerates the Protein Aggregation via the Downhill Polymerization Mechanism: Multi-Spectroscopic Studies to Delineate the Implications on Proteinopathies

[Image: see text] Heparin is one of the members of the glycosaminoglycan (GAG) family, which has been associated with protein aggregation diseases including Alzheimer’s disease, Parkinson’s disease, and prion diseases. Here, we investigate heparin-induced aggregation of bovine serum albumin (BSA) us...

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Detalhes bibliográficos
Publicado no:ACS Omega
Main Authors: Ahanger, Ishfaq Ahmad, Parray, Zahoor Ahmad, Nasreen, Khalida, Ahmad, Faizan, Hassan, Md. Imtaiyaz, Islam, Asimul, Sharma, Anurag
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2021
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7841943/
https://ncbi.nlm.nih.gov/pubmed/33521471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.0c05638
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