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Heparin Accelerates the Protein Aggregation via the Downhill Polymerization Mechanism: Multi-Spectroscopic Studies to Delineate the Implications on Proteinopathies

[Image: see text] Heparin is one of the members of the glycosaminoglycan (GAG) family, which has been associated with protein aggregation diseases including Alzheimer’s disease, Parkinson’s disease, and prion diseases. Here, we investigate heparin-induced aggregation of bovine serum albumin (BSA) us...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:ACS Omega
Prif Awduron: Ahanger, Ishfaq Ahmad, Parray, Zahoor Ahmad, Nasreen, Khalida, Ahmad, Faizan, Hassan, Md. Imtaiyaz, Islam, Asimul, Sharma, Anurag
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Chemical Society 2021
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7841943/
https://ncbi.nlm.nih.gov/pubmed/33521471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.0c05638
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