Nanoparticle-Mediated Delivery of 2-Deoxy-D-Glucose Induces Antitumor Immunity and Cytotoxicity in Liver Tumors in Mice

BACKGROUND & AIMS: Immune checkpoint inhibitors have shed light on the importance of antitumor immunity as a therapeutic strategy for hepatocellular carcinoma (HCC). The altered glucose metabolism known as the Warburg effect recently has gained attention as a cancer immune-resistance mechanism....

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Vydáno v:Cell Mol Gastroenterol Hepatol
Hlavní autoři: Sasaki, Kyo, Nishina, Sohji, Yamauchi, Akira, Fukuda, Kotaro, Hara, Yuichi, Yamamura, Masahiro, Egashira, Kensuke, Hino, Keisuke
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2020
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7841526/
https://ncbi.nlm.nih.gov/pubmed/33191170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2020.10.010
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