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Inhibition of MMP-2 Expression Enhances the Antitumor Effect of Sorafenib in Hepatocellular Carcinoma by Suppressing the PI3K/AKT/mTOR Pathway

Sorafenib has been globally approved as the standard treatment for patients with advanced hepatocellular carcinoma (HCC). However, the response rate of HCC patients to sorafenib is limited because of tumor recurrence and metastasis. Therefore, seeking combined therapeutic strategies with sorafenib i...

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Bibliografiska uppgifter
I publikationen:Oncol Res
Huvudupphovsmän: Tan, Wenliang, Zhu, Sicong, Cao, Jun, Zhang, Lei, Li, Wenda, Liu, Kairui, Zhong, Jinyi, Shang, Changzhen, Chen, Yajin
Materialtyp: Artigo
Språk:Inglês
Publicerad: Cognizant Communication Corporation 2017
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7841021/
https://ncbi.nlm.nih.gov/pubmed/28276313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3727/096504017X14886444100783
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