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Fluorescent thermal shift-based method for detection of NF-κB binding to double-stranded DNA

The nuclear factor kappa B (NF-κB) family of dimeric transcription factors regulates a wide range of genes by binding to their specific DNA regulatory sequences. NF-κB is an important therapeutic target linked to a number of cancers as well as autoimmune and inflammatory diseases. Therefore, effecti...

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Vydáno v:Sci Rep
Hlavní autoři: Leitner, Peter D., Vietor, Ilja, Huber, Lukas A., Valovka, Taras
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7840993/
https://ncbi.nlm.nih.gov/pubmed/33504856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-81743-1
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