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Architecture of the Tuberous Sclerosis Protein Complex
The Tuberous Sclerosis Complex (TSC) protein complex (TSCC), comprising TSC1, TSC2, and TBC1D7, is widely recognised as a key integration hub for cell growth and intracellular stress signals upstream of the mammalian target of rapamycin complex 1 (mTORC1). The TSCC negatively regulates mTORC1 by act...
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| 發表在: | J Mol Biol |
|---|---|
| Main Authors: | , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Elsevier
2021
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7840889/ https://ncbi.nlm.nih.gov/pubmed/33307091 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2020.166743 |
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