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Lateral habenula dysfunctions in Tm4sf2(−/y) mice model for neurodevelopmental disorder

Mutations in the TM4SF2 gene, which encodes TSPAN7, cause a severe form of intellectual disability (ID) often comorbid with autism spectrum disorder (ASD). Recently, we found that TM4SF2 loss in mice affects cognition. Here, we report that Tm4sf2(−/y) mice, beyond an ID-like phenotype, display alter...

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Bibliografiske detaljer
Udgivet i:Neurobiol Dis
Main Authors: Murru, Luca, Ponzoni, Luisa, Longatti, Anna, Mazzoleni, Sara, Giansante, Giorgia, Bassani, Silvia, Sala, Mariaelvina, Passafaro, Maria
Format: Artigo
Sprog:Inglês
Udgivet: Academic Press 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7840593/
https://ncbi.nlm.nih.gov/pubmed/33227491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2020.105189
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