A Type 2 Deiodinase-Dependent Increase in Vegfa Mediates Myoblast-Endothelial Cell Crosstalk During Skeletal Muscle Regeneration

Background: The type 2 deiodinase (DIO2) converts thyroxine to 3,3′,5-triiodothyronine (T3), modulating intracellular T3. An increase in DIO2 within muscle stem cells during skeletal muscle regeneration leads to T3-dependent potentiation of differentiation. The muscle stem cell niche comprises numer...

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Detalhes bibliográficos
Publicado no:Thyroid
Main Authors: An, Xingxing, Ogawa-Wong, Ashley, Carmody, Colleen, Ambrosio, Raffaele, Cicatiello, Annunziata Gaetana, Luongo, Cristina, Salvatore, Domenico, Handy, Diane E., Larsen, P. Reed, Wajner, Simone Magagnin, Dentice, Monica, Zavacki, Ann Marie
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc., publishers 2021
Assuntos:
Thyroid Economy: Regulation, Cell Biology, and Thyroid Hormone Metabolism and Action
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7840309/
https://ncbi.nlm.nih.gov/pubmed/32787533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/thy.2020.0291
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