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CYLD alterations in the tumorigenesis and progression of human papillomavirus-associated head and neck cancers

Genetic alterations of CYLD lysine 63 deubiquitinase (CYLD), a tumor suppressor gene encoding a deubiquitinase (DUB) enzyme, are associated with the formation of tumors in CYLD cutaneous syndrome. Genome sequencing efforts have revealed somatic CYLD alterations in multiple human cancers. Moreover, i...

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Detalhes bibliográficos
Publicado no:Mol Cancer Res
Main Authors: Cui, Zhibin, Kang, Hyunseok, Grandis, Jennifer R., Johnson, Daniel E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7840145/
https://ncbi.nlm.nih.gov/pubmed/32883697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-20-0565
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