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The keratin network of intermediate filaments regulates keratinocyte rigidity sensing and nuclear mechanotransduction

The keratin network of intermediate filaments provides keratinocytes with essential mechanical strength and resilience, but the contribution to mechanosensing remains poorly understood. Here, we investigated the role of the keratin cytoskeleton in the response to altered matrix rigidity. We found th...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Laly, Ana C., Sliogeryte, Kristina, Pundel, Oscar J., Ross, Rosie, Keeling, Michael C., Avisetti, Deepa, Waseem, Ahmad, Gavara, Núria, Connelly, John T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7840118/
https://ncbi.nlm.nih.gov/pubmed/33571121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abd6187
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