The keratin network of intermediate filaments regulates keratinocyte rigidity sensing and nuclear mechanotransduction

The keratin network of intermediate filaments provides keratinocytes with essential mechanical strength and resilience, but the contribution to mechanosensing remains poorly understood. Here, we investigated the role of the keratin cytoskeleton in the response to altered matrix rigidity. We found th...

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Bibliografische gegevens
Gepubliceerd in:Sci Adv
Hoofdauteurs: Laly, Ana C., Sliogeryte, Kristina, Pundel, Oscar J., Ross, Rosie, Keeling, Michael C., Avisetti, Deepa, Waseem, Ahmad, Gavara, Núria, Connelly, John T.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Association for the Advancement of Science 2021
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Research Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7840118/
https://ncbi.nlm.nih.gov/pubmed/33571121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abd6187
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