The keratin network of intermediate filaments regulates keratinocyte rigidity sensing and nuclear mechanotransduction

The keratin network of intermediate filaments provides keratinocytes with essential mechanical strength and resilience, but the contribution to mechanosensing remains poorly understood. Here, we investigated the role of the keratin cytoskeleton in the response to altered matrix rigidity. We found th...

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Publicado en:Sci Adv
Autores principales: Laly, Ana C., Sliogeryte, Kristina, Pundel, Oscar J., Ross, Rosie, Keeling, Michael C., Avisetti, Deepa, Waseem, Ahmad, Gavara, Núria, Connelly, John T.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Association for the Advancement of Science 2021
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7840118/
https://ncbi.nlm.nih.gov/pubmed/33571121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abd6187
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