Standard Anthracycline Based Versus Docetaxel-Capecitabine in Early High Clinical and/or Genomic Risk Breast Cancer in the EORTC 10041/BIG 3-04 MINDACT Phase III Trial

PURPOSE: MINDACT demonstrated that 46% of patients with early breast cancer at high clinical but low genomic risk on the basis of MammaPrint may safely avoid adjuvant chemotherapy. A second random assignment (R-C) compared docetaxel-capecitabine with an anthracycline-based regimen. PATIENTS AND METH...

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Udgivet i:J Clin Oncol
Main Authors: Delaloge, Suzette, Piccart, Martine, Rutgers, Emiel, Litière, Saskia, van ’t Veer, Laura J., van den Berkmortel, Franchette, Brain, Etienne, Dudek-Peric, Aleksandra, Gil-Gil, Miguel, Gomez, Patricia, Hilbers, Florentine S., Khalil, Zaman, Knox, Susan, Kuemmel, Sherko, Kunz, Georg, Lesur, Anne, Pierga, Jean-Yves, Ravdin, Peter, Rubio, Isabel T., Saghatchian, Mahasti, Smilde, Tineke J., Thompson, Alastair M., Viale, Giuseppe, Zoppoli, Gabriele, Vuylsteke, Peter, Tryfonidis, Konstantinos, Poncet, Coralie, Bogaerts, Jan, Cardoso, Fatima
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Clinical Oncology 2020
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ORIGINAL REPORTS
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7840116/
https://ncbi.nlm.nih.gov/pubmed/32083990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.19.01371
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