Germline copy number variations in BRCA1/2 negative families: Role in the molecular etiology of hereditary breast cancer in Tunisia

Hereditary breast cancer accounts for 5–10% of all breast cancer cases. So far, known genetic risk factors account for only 50% of the breast cancer genetic component and almost a quarter of hereditary cases are carriers of pathogenic mutations in BRCA1/2 genes. Hence, the genetic basis for a signif...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Boujemaa, Maroua, Hamdi, Yosr, Mejri, Nesrine, Romdhane, Lilia, Ghedira, Kais, Bouaziz, Hanen, El Benna, Houda, Labidi, Soumaya, Dallali, Hamza, Jaidane, Olfa, Ben Nasr, Sonia, Haddaoui, Abderrazek, Rahal, Khaled, Abdelhak, Sonia, Boussen, Hamouda, Boubaker, Mohamed Samir
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7840007/
https://ncbi.nlm.nih.gov/pubmed/33503040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0245362
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