Identification of Novel BRCA1 and RAD50 Mutations Associated With Breast Cancer Predisposition in Tunisian Patients

BACKGROUND: Deleterious mutations on BRCA1/2 genes are known to confer high risk of developing breast and ovarian cancers. The identification of these mutations not only helped in selecting high risk individuals that need appropriate prevention approaches but also led to the development of the PARP-...

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Bibliografske podrobnosti
izdano v:Front Genet
Main Authors: Mighri, Najah, Hamdi, Yosr, Boujemaa, Maroua, Othman, Houcemeddine, Ben Nasr, Sonia, El Benna, Houda, Mejri, Nesrine, Labidi, Soumaya, Ayari, Jihen, Jaidene, Olfa, Bouaziz, Hanen, Ben Rekaya, Mariem, M’rad, Ridha, Haddaoui, Abderrazek, Rahal, Khaled, Boussen, Hamouda, Boubaker, Samir, Abdelhak, Sonia
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2020
Teme:
Genetics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7677579/
https://ncbi.nlm.nih.gov/pubmed/33240314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2020.552971
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