Identification of Novel BRCA1 and RAD50 Mutations Associated With Breast Cancer Predisposition in Tunisian Patients

BACKGROUND: Deleterious mutations on BRCA1/2 genes are known to confer high risk of developing breast and ovarian cancers. The identification of these mutations not only helped in selecting high risk individuals that need appropriate prevention approaches but also led to the development of the PARP-...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Mighri, Najah, Hamdi, Yosr, Boujemaa, Maroua, Othman, Houcemeddine, Ben Nasr, Sonia, El Benna, Houda, Mejri, Nesrine, Labidi, Soumaya, Ayari, Jihen, Jaidene, Olfa, Bouaziz, Hanen, Ben Rekaya, Mariem, M’rad, Ridha, Haddaoui, Abderrazek, Rahal, Khaled, Boussen, Hamouda, Boubaker, Samir, Abdelhak, Sonia
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Genetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7677579/
https://ncbi.nlm.nih.gov/pubmed/33240314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2020.552971
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