Enzymatic Noncovalent Synthesis for Mitochondrial Genetic Engineering of Cancer Cells

Since mitochondria contribute to tumorigenesis and drug resistance in cancer, mitochondrial genetic engineering promises a new direction for cancer therapy. Here, we report the use of the perimitochondrial enzymatic noncovalent synthesis (ENS) of peptides for delivering genes selectively into the mi...

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Udgivet i:Cell Rep Phys Sci
Main Authors: He, Hongjian, Lin, Xinyi, Wu, Difei, Wang, Jiaqing, Guo, Jiaqi, Green, Douglas R., Zhang, Hongwei, Xu, Bing
Format: Artigo
Sprog:Inglês
Udgivet: 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7839975/
https://ncbi.nlm.nih.gov/pubmed/33511360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xcrp.2020.100270
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