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A Thermodynamic Perspective on Potential G‐Quadruplex Structures as Silencer Elements in the MYC Promoter

Multiple G‐tracts within the promoter region of the c‐myc oncogene may fold into various G‐quadruplexes with the recruitment of different tracts and guanosine residues for the G‐core assembly. Thermodynamic profiles for the folding of wild‐type and representative truncated as well as mutated sequenc...

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Dades bibliogràfiques
Publicat a:Chemistry
Autors principals: Jana, Jagannath, Weisz, Klaus
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7839732/
https://ncbi.nlm.nih.gov/pubmed/32761687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.202002985
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