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Structural insight for the recognition of G-quadruplex structure at human c-myc promoter sequence by flavonoid Quercetin

Small molecule ligands that could stabilize G-quadruplex structure formed at the promoter region of human c-myc oncogene will regulate its expression in cancer cells. Flavonoids, a group of naturally available small molecule, have been known for their various promising effects on human health. In pr...

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Pubblicato in:Sci Rep
Autori principali: Tawani, Arpita, Mishra, Subodh Kumar, Kumar, Amit
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5472631/
https://ncbi.nlm.nih.gov/pubmed/28620169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-03906-3
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