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Autophagy in white matter disorders of the CNS: mechanisms and therapeutic opportunities

Autophagy is a constitutive process that degrades, recycles and clears damaged proteins or organelles, yet, despite activation of this pathway, abnormal proteins accumulate in neurons in neurodegenerative diseases and in oligodendrocytes in white matter disorders. Here, we discuss the role of autoph...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Pathol
Main Authors: Nutma, Erik, Marzin, Manuel C, Cillessen, Saskia AGM, Amor, Sandra
Format: Artigo
Jezik:Inglês
Izdano: John Wiley & Sons, Ltd 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7839724/
https://ncbi.nlm.nih.gov/pubmed/33135781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.5576
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