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Autophagy in white matter disorders of the CNS: mechanisms and therapeutic opportunities

Autophagy is a constitutive process that degrades, recycles and clears damaged proteins or organelles, yet, despite activation of this pathway, abnormal proteins accumulate in neurons in neurodegenerative diseases and in oligodendrocytes in white matter disorders. Here, we discuss the role of autoph...

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Detalhes bibliográficos
Publicado no:J Pathol
Main Authors: Nutma, Erik, Marzin, Manuel C, Cillessen, Saskia AGM, Amor, Sandra
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7839724/
https://ncbi.nlm.nih.gov/pubmed/33135781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.5576
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