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A review on age‐related cancer risks in PTEN hamartoma tumor syndrome

Patients with PTEN hamartoma tumor syndrome (PHTS, comprising Cowden, Bannayan‐Riley‐Ruvalcaba, and Proteus‐like syndromes) are at increased risk of developing cancer due to pathogenic PTEN germline variants. This review summarizes age‐, sex‐, and type‐specific malignant cancer risks for PHTS patien...

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Détails bibliographiques
Publié dans:Clin Genet
Auteurs principaux: Hendricks, Linda A.J., Hoogerbrugge, Nicoline, Schuurs‐Hoeijmakers, Janneke H.M., Vos, Janet R.
Format: Artigo
Langue:Inglês
Publié: Blackwell Publishing Ltd 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7839546/
https://ncbi.nlm.nih.gov/pubmed/33140411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cge.13875
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