Specialist oncological surgery for removal of the ovaries and fallopian tubes in BRCA1 and BRCA2 pathogenic variant carriers may reduce primary peritoneal cancer risk to very low levels

Risk‐reducing bilateral salpingo‐oophorectomy (RRBSO) is highly effective for the prevention of high‐grade serous ovarian cancer (HGSOC) in BRCA1/2 pathogenic variant carriers (PVCs), but does not completely eliminate future risk of primary peritoneal cancer (PPC). The requirement to completely remo...

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Vydáno v:Int J Cancer
Hlavní autoři: Crosbie, Emma J., Flaum, Nicola, Harkness, Elaine F., Clayton, Richard D., Holland, Cathrine, Martin‐Hirsch, Pierre, Wood, Nick, Keating, Patrick, Woodward, Emma R., Lalloo, Fiona, Donnai, Paul, Edmondson, Richard J., Evans, D. Gareth
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley & Sons, Inc. 2020
Témata:
Cancer Genetics and Epigenetics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7839461/
https://ncbi.nlm.nih.gov/pubmed/33152107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.33378
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