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Rapid removal of phagosomal ferroportin in macrophages contributes to nutritional immunity

Nutrient sequestration is an essential facet of host innate immunity. Macrophages play a critical role in controlling iron availability through expression of the iron transport protein ferroportin (FPN), which extrudes iron from the cytoplasm to the extracellular milieu. During phagocytosis, the lim...

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Détails bibliographiques
Publié dans:Blood Adv
Auteurs principaux: Flannagan, Ronald S., Farrell, Tayler J., Trothen, Steven M., Dikeakos, Jimmy D., Heinrichs, David E.
Format: Artigo
Langue:Inglês
Publié: American Society of Hematology 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7839378/
https://ncbi.nlm.nih.gov/pubmed/33496744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020002833
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