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New structural insights reveal an expanded reaction cycle for inositol pyrophosphate hydrolysis by human DIPP1.

Nudix hydrolases attract considerable attention for their wide range of specialized activities in all domains of life. One particular group of Nudix phosphohydrolases (DIPPs), through their metabolism of diphosphoinositol polyphosphates (PP-InsPs), regulates the actions of these polyphosphates upon...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Zong, Guangning, Jork, Nikolaus, Hostachy, Sarah, Fiedler, Dorothea, Jessen, Henning J., Shears, Stephen B., Wang, Huanchen
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7839254/
https://ncbi.nlm.nih.gov/pubmed/33475202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.202001489R
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