Fluorination Influences the Bioisostery of Myo‐Inositol Pyrophosphate Analogs

Inositol pyrophosphates (PP−IPs) are densely phosphorylated messenger molecules involved in numerous biological processes. PP−IPs contain one or two pyrophosphate group(s) attached to a phosphorylated myo‐inositol ring. 5PP−IP(5) is the most abundant PP−IP in human cells. To investigate the function...

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Bibliographic Details
Published in:Chemistry
Main Authors: Hostachy, Sarah, Wang, Huanchen, Zong, Guangning, Franke, Katy, Riley, Andrew M., Schmieder, Peter, Potter, Barry V. L., Shears, Stephen B., Fiedler, Dorothea
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2023
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7615343/
https://ncbi.nlm.nih.gov/pubmed/37773020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.202302426
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