Outcomes of Venetoclax and BCR-ABL Tyrosine Kinase Inhibitor Combinations in Patients with Philadelphia Chromosome-Positive Advanced Myeloid Leukemias

BACKGROUND: Philadelphia chromosome-positive (Ph+) advanced leukemias including acute myeloid leukemia (AML) and chronic myeloid leukemia myeloid blast phase (CML-MBP) have poor outcomes. Venetoclax (VEN) has shown synergism with BCR-ABL1 tyrosine kinase inhibitors (TKI) in pre-clinical studies. How...

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Pubblicato in:Acta Haematol
Autori principali: Maiti, Abhishek, Franquiz, Miguel, Ravandi, Farhad, Cortes, Jorge E., Jabbour, Elias J., Sasaki, Koji, Marx, Kayleigh, Daver, Naval G., Kadia, Tapan M., Konopleva, Marina Y., Masarova, Lucia, Borthakur, Gautam, DiNardo, Courtney D., Naqvi, Kiran, Pierce, Sherry, Kantarjian, Hagop M., Short, Nicholas J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7839068/
https://ncbi.nlm.nih.gov/pubmed/32289808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000506346
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